Corin Overexpression Reduces Myocardial Infarct Size and Modulates Cardiomyocyte Apoptotic Cell Death.

WT hearts post-MI although it did not reach statistical significance ( p > 0.05, Figure 4 E).

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Both Akt and Bad showed a trend to enhanced phosphorylation in corin-Tg mice when compared with WT mice ( Figure 5 A); however, only the increased phosphorylation of Akt was statistically significant ( Figure 5 B, 1.9 ± 0.3 vs. 1.0 ± 0.1, p < 0.05) while the phosphorylation of Bad was not ( Figure 5 C, 1.6 ± 0.5 vs. 1.0 ± 0.1, p > 0.05).

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