As seen in Figure 5A , CD8+ T cells from the cervix of postmenopausal women showed a significant decrease in GZB and a strong trend toward increased GZA, regardless of CD103+ or CD103− expression.
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Differential Cytotoxic Function of Resident and Non-resident CD8+ T Cells in the Human Female Reproductive Tract Before and After Menopause.
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As shown in Figure 6E , after 4 days of proliferation, CD103+ T cells had increased ability to produce three cytotoxic molecules (perforin, GZA and GZB) when compared to CD103− T cells, although this difference did not reach statistical significance.