Interestingly, in line with higher inflammatory markers in men with metabolic syndrome, there is a strong trend toward higher monocyte-derived inflammatory cytokine production capacity specifically in men, but not women, with metabolic syndrome (Figure 4 A, left, Figure 4B, Tables XII and XIII in the Data Supplement ).
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Sex-Specific Regulation of Inflammation and Metabolic Syndrome in Obesity.
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The top pathway found in a pathway analysis was valine, leucine, and isoleucine biosynthesis though it did not reach statistical significance after multiple testing correction (Table XVII in the Data Supplement ).