Glutamic acid decarboxylase 67 haplodeficiency in mice: consequences of postweaning social isolation on behavior and changes in brain neurochemical systems.

Post hoc analyses for isolated GAD67 + /GFP mice, compared with isolated GAD67 + / + mice, showed a trend towards a lower time spent in social contact ( t = − 2.02, df = 15, p = 0.062, Fig. 1 a) and significantly less time spent in passive social interaction ( t = − 2.32, df = 15, p < 0.05, Fig. 1 b), indicating that post-weaning social isolation affects social behavior in GAD67 + /GFP mice.

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However, the post hoc analyses did not reach statistical significance (n.s.).

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