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Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells.

J Exp Med · 2020 · PMC7336313 · PMID 32374402

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showed a trendno p-value reported
We found that inactivation of Prdm1 in Hdac3- KO CD8 T cells showed a trend toward improved persistence compared with Hdac3- WT CD8 T cells, but this effect did not reach statistical significance in all experiments (pooled data shown in Fig. 7 C ).

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