Even though this decrease did not reach statistical significance in the whole cohort, subgroup analysis showed that the decreases were significant in patients with high VEGFR2 expression (93% vs. 67.7%, p = 0.012), or positive kinase-insert domain-containing receptor expression (94.4% vs. 47.3%, p = 0.002) [ 13 ].
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Current Status and Study Progress of Recombinant Human Endostatin in Cancer Treatment.
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It also showed a trend in improving PFS and ORR, but not OS.