highly significantp = 1.1e− 22
In the final combined analysis, there was highly significant evidence for association with MS in this region ( p = 1.1e− 22).
In the final combined analysis, there was highly significant evidence for association with MS in this region ( p = 1.1e− 22).
Six of these SNPs showed genome-wide significant evidence for association in one of the studies with concordant and nominally significant effects in the second study.
We observed a similar trend in MMP2 secretion; however, this did not reach statistical significance (Fig. 6 c).