Intrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45<sup>low</sup>CD271<sup>+</sup> Multipotential Stromal Cells (BM-MSCs): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation.

Biomedicines · 2020 · PMC7399891 · PMID 32679782

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showed a trendno p-value reported

IL7 transcript showed a trend for downregulation in BM-MSCs from OA patients in parallel with significant downregulation of several ISGs including IFITM1, IFITM3 and USP18; this pointed towards potential involvement of IFN1 signalling pathway in IL7 transcriptional regulation in OA.

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failed to reach statistical significanceno p-value reported

The expression of SIRT6 was higher in BM-MSCs in most donors, but the differences failed to reach statistical significance ( Figure 4 a).

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