Micro-dystrophin AAV Vectors Made by Transient Transfection and Herpesvirus System Are Equally Potent in Treating mdx Mouse Muscle Disease.

Qualitative evaluation of the H&E-stained images showed a clear trend of dose-dependent improvement of the histology in AAV-injected mdx4cv mice ( Figure 5 A).

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The medium-dose group appeared to have more vector genome copies than that of the low-dose group, but the difference did not reach statistical significance ( Figure 4 ).

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