Safety and tolerability of PD-1/PD-L1 inhibitors in elderly and frail patients with advanced malignancies.

Oncol Lett · 2020 · PMC7406883 · PMID 32774487

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

close to significanceP=0.08so close (0.05 < p ≤ 0.1)

The proportion of patients with high frailty was considerably greater in the elderly group and close to significance (P=0.08).

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did not reach statistical significanceno p-value reported

A certain deviation in tumor type was observed, and the elderly group showed fewer prior therapy lines and higher CCI scores, although these did not reach statistical significance.

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showed a trendno p-value reported

Sattar et al ( 29 ) and Leroy et al ( 30 ) showed a trend of higher incidence of irAEs in elderly patients.

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