Risk factors and outcome of COVID-19 in patients with hematological malignancies.

Due to the lack of data in up to half of our patients, we were unable to analyze the impact of other inflammatory/procoagulant biomarkers, such as ferritin, IL-6 and D-dimer on the risk of developing severe pneumonia and death, although they did show a clear trend in univariate analysis (as shown in Table 2 ).

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In such real-life setting, COVID-19 mortality was mainly driven by advanced age, poor performance status, uncontrolled disease status (not being at least in a partial remission), presence of marrow or immune failure (severe neutropenia, and lymphopenia in the univariate analysis) and having a high baseline and/or COVID-19 induced systemic inflammatory state (identified in the multivariate analysis by high CRP, although high levels of IL-6 and ferritin showed a strong trend in univariate analysis).

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