Novel fractionated ultrashort thermal exposures with MRI-guided focused ultrasound for treating tumors with thermosensitive drugs.

Sci Adv · 2020 · PMC7467687 · PMID 32917589

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.1700

boldest claim

The sentences

approached significanceP = 0.06so close (0.05 < p ≤ 0.1)

However, the drug signal level was significantly elevated at 42°C versus 41°C (74 ± 17% versus 21 ± 9% I 0 , * P = 0.03) and at 43°C, the drug signal approached significance compared to 41°C (67 ± 33% versus 21 ± 9% I 0 , P = 0.06).

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did not reach statistical significanceP = 0.17not close (p > 0.1)

A quantitative intergroup analysis of variance (ANOVA) of the area under the curve from 0 to 60 min for the different groups did not reach statistical significance ( P = 0.17).

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