Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients.

As in adults, QAlb was positively linked to the spinal cord lesion load as detected by MRI and measured in VS in patients with acute myelitis ( r 2 = 0.175); however, the correlation did not reach statistical significance ( p = 0.053) (Fig. 4 ).

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CSF lactate levels showed a trend toward lower values with increasing time (in days) since onset of the last attack ( p = 0.055) (Fig. 3 ).

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When considering not only the presence or absence of neutrophils but absolute neutrophil numbers, a weak trend toward a correlation ( p = 0.067) was found between CSF l -lactate levels and neutrophil cell numbers in the small subgroup of samples with available data ( N = 19); however, this was neither seen in the adult cohort nor in a pooled analysis of the pediatric and the adult data.

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The difference between the acute MY and the acute ON group remained highly significant also when applying the 35 mg/dl cut-off or the age-partitioned cut-off intervals proposed by Kahlmann et al.

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