Preoperative myocardial expression of E3 ubiquitin ligases in aortic stenosis patients undergoing valve replacement and their association to postoperative hypertrophy.

PLoS One · 2020 · PMC7500680 · PMID 32946439

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

approaching significancep = 0.10so close (0.05 < p ≤ 0.1)

Concerning LVM regression, the most important parameter to determine the success of AVR in patients’ outcome, out of the five UPS elements analyzed, MDM2 showed the strongest association (r = -0.44), approaching significance ( p = 0.10).

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marginally significantp ≤ 0.10so close (0.05 < p ≤ 0.1)

In this version we addressed the two points raised during the revision process, namely data duplication (figure 2 was eliminated, table 3 was maintained) and data display on table 3, which now depicts only significant (p < 0.05) and marginally significant (p ≤ 0.10) correlations.

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did not reach statistical significanceno p-value reported

Surprisingly, no differences were found for these UPS players, despite the apparently higher levels of MuRF3 (1.3-fold, p = 0.17) in cRR patients, which did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.