Is intravenous lidocaine protective against myocardial ischaemia and reperfusion injury after cardiac surgery?

Ann Med Surg (Lond) · 2020 · PMC7501487 · PMID 32994986

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

a clear trendp = 0.09so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

There was a clear trend towards lower CK-MB (p = 0.09), Troponin T (TnT) values (p = 0.06) and myocardial infarctions (p = 0.20) in the lidocaine treated group, but these did not reach statistical significance ( Table 1 ).

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marginally non-significantno p-value reported

An additional study lacked power, but the difference in biomarkers was marginally non-significant with a trend in favour of lidocaine.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.