No significant differences between PC storage times < 4 months were observed in terms of HPL cytokine concentrations, i.e., a clear trend for cytokine deterioration with time, or corresponding MSC proliferation and osteogenic differentiation.
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Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering.
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The sentences
When analyzing data from individual donors, some differences in ALP activity and mineralization were observed, i.e., BMSCs from the same donor showed different activities in HPLs from different PC storage times, although these differences did not reach statistical significance for any of the donors.