A polymorphism in the cachexia-associated gene INHBA predicts efficacy of regorafenib in patients with refractory metastatic colorectal cancer.

PLoS One · 2020 · PMC7514061 · PMID 32970737

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did not reach statistical significanceno p-value reported

However, these differences did not reach statistical significance, indicating that INHBA rs2237432 has a specific association with regorafenib efficacy.

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showed a trendno p-value reported

In the TAS-102 cohort, contrary to the regorafenib cohort, INHBA rs2237432 at any G allele showed a trend toward worse PFS and OS compared with that at the A/A allele.

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