Inhaled dry powder alginate oligosaccharide in cystic fibrosis: a randomised, double-blind, placebo-controlled, crossover phase 2b study.

ERJ Open Res · 2020 · PMC7569163 · PMID 33123558

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

did not reach statistical significancep=0.07so close (0.05 < p ≤ 0.1)

There was a trend towards improvement in FEV 1 which did not reach statistical significance, after OligoG treatment in those patients who took less than the full dose of the drug (<100% compliance), with 5.5% improvement in FEV 1 at day 28 (p=0.07), and 8.5% improvement in FEV 1 at day 56 (p=0.07).

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showed a trendno p-value reported

An analysis of peripheral lung clearance, which is less confounded by deposition changes, showed a trend towards faster peripheral lung clearance with OligoG.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.