Metabolic Syndrome Triggered by Fructose Diet Impairs Neuronal Function and Vascular Integrity in ApoE-KO Mouse Retinas: Implications of Autophagy Deficient Activation.

Regarding the total cholesterol levels, a clearly significant difference was observed between ApoE-KO and WT mice, independently of the diet, at every evaluated time point ( Figure 1B , p < 0.0001).

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A similar trend was seen for protein levels of LC3BII, where this difference did not reach statistical significance ( Figure 4B ), correlating with the qRT-PCR data.

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