Transcriptome Profiling Reveals New Insights into the Immune Microenvironment and Upregulation of Novel Biomarkers in Metastatic Uveal Melanoma.

Cancers (Basel) · 2020 · PMC7650807 · PMID 33008022

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

showed a trendno p-value reported

The BCL-2/XL/W inhibitor (ABT263) combined with MDM2 inhibitor (HDM201) showed a trend for a synergistic effect in the PDX models [ 106 ].

also in 53,322 other papers

did not reach statistical significanceno p-value reported

Upregulation of gene markers of cytotoxic cells, macrophages, DCs, and exhausted CD8+ T-cells was observed, although they did not reach statistical significance ( Table S2A ).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.