Utility of shape evolution and displacement in the classification of chronic multiple sclerosis lesions.

Positive surface area changes in the SVD group (95% CrI = (− 0.56, 5.18), Bayesian p value = 0.12) and negative changes in the MS cohort (95% CrI = (− 3.03, 1.13), p = 0.34) that did not reach statistical significance were identified after controlling for age, surface area of the given lesion at baseline, and duration between MRI studies.

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We identified a significant reduction in volume and a reduction in surface area trending towards significance in MS lesions.

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