NK cell infiltration is associated with improved overall survival in solid cancers: A systematic review and meta-analysis.

Although studies staining for NKp46 also revealed a significant trend, the prognostic value was weaker 41 , 51 , 65 , 77 ( n = 4, HR=0.64, 95% CI: 0.41–1.00; p = 0.020) ( Fig. 5 B).

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Breast cancer is a multi-faceted disease with significant heterogeneity and as such, it is not surprising that a clear trend was not observed, therefore, further analysis with stratification by subtype may provide a clearer association.

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