showed a trendP = 0.0956
Compared with antidiabetic therapy alone, the use of EPL plus antidiabetic therapy significantly reduced the likelihood of having moderate disease [RR: 0.52 (95%CI: 0.30, 0.90); P = 0.0187; I 2 = 0.0%; Figure 2F ] and showed a trend towards a reduced risk of severe disease [RR: 0.34 (95%CI: 0.10, 1.21); P = 0.0956; I 2 = 0.0%], but no impact on the incidence of mild disease [RR: 1.16 (95%CI: 0.56, 2.39); P = 0.6862; I 2 = 63.5%; Figure 2F ).