DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR<sup>-</sup> myeloid cells, compared with HLA-DR<sup>+</sup> antigen-presenting cells.

Epigenetics · 2020 · PMC7678924 · PMID 32419601

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

Moreover, the mRNA level of TET2 was also high in CD33 + HLA-DR – cells, compared to CD33 + HLA-DR + cells, but did not reach statistical significance ( P = 0.06, Figure 2(b )).

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showed a trendno p-value reported

TGF-β1 promoter showed a trend towards an increased percentage of unmethylation in CD33 + HLA-DR – cells, but the data were not statistically significant ( P = 0.08, Figure 3(d ) & (h) ).

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