Patterns of anticoagulation therapy in atrial fibrillation: results from a large real-life single-center registry.

Croat Med J · 2020 · PMC7684544 · PMID 33150762

Europe PMC

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did not reach statistical significanceno p-value reported

After adjusting analyses for sex and BMI (unbalanced at baseline between DOAC subclasses), difference in TTT among three DOAC subclasses did not reach statistical significance.

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a significant trendno p-value reported

There was a significant trend of increase in the frequency of DOAC use over time, and the penetration of DOACs reached 62% by the end of 2018 (P for trend = 0.002).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.