Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington's disease for participants of varying functional disability: a pilot study.

Sci Rep · 2020 · PMC7686309 · PMID 33235276

Europe PMC DOI

hedged sentences

0.0676

closest p · 1.4× alpha

0.0676

boldest claim

The sentences

a negative trendp = 0.0676so close (0.05 < p ≤ 0.1)

a positive trendp = 0.073so close (0.05 < p ≤ 0.1)

Hexose demonstrated a positive trend with TFC ( p = 0.073), IND ( p = 0.0797), and a negative trend with TMS ( p = 0.0676) suggesting lower levels with disease progression, though a contrasting positive correlation with Behavior scores ( p = 0.037) was observed.

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nominally significantno p-value reported

With disease progression, we observed nominally significant increases in plasma arginine, citrulline, and glycine, with decreases in total and d -serine, cholesterol esters, diacylglycerides, triacylglycerides, phosphatidylcholines, phosphatidylethanolamines, and sphingomyelins.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.