Biological Aging Marker p16<sup>INK4a</sup> in T Cells and Breast Cancer Risk.

Cancers (Basel) · 2020 · PMC7692397 · PMID 33114473

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0530

boldest claim

The sentences

a significant trendp < 0.001actually significant

In addition, a significant trend of increasing risk of breast cancer was observed when p16 INK4a mRNA expression increased ( p < 0.001).

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marginally significantp = 0.053so close (0.05 < p ≤ 0.1)

A marginally significant association was further observed in the validation stage with 47 cases and 48 controls using pre-diagnostic samples (OR = 1.28; 95%CI: 0.98, 2.97; p = 0.053).

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did not reach statistical significanceno p-value reported

A similar trend was also observed for education, with lower education having higher p16 INK4a mRNA expression, but the difference did not reach statistical significance.

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