Evaluation for the Genetic Association between Store-Operated Calcium Influx Pathway (STIM1 and ORAI1) and Human Hepatocellular Carcinoma in Patients with Chronic Hepatitis B Infection.

Biology (Basel) · 2020 · PMC7695319 · PMID 33182378

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a borderline significant trendno p-value reported

Although genetic polymorphisms of the SOC pathway ( STIM1 and ORAI1 ) are not significantly associated with HCC progression after multiple correction, three SNPs of STIM1 (rs6578418, rs11030472, and rs7116520) and one SNP of ORAI1 (rs6486795) showed a borderline significant trend that should be particularly focused on in future studies.

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showed a trendno p-value reported

Three single-nucleotide polymorphisms (SNPs) of STIM1 (rs6578418, rs11030472, and rs7116520) and one SNP of ORAI1 (rs6486795) showed a trend of being significantly associated with HCC.

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