Cerebral small vessel disease genomics and its implications across the lifespan.

Nat Commun · 2020 · PMC7722866 · PMID 33293549

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

The WMH wGRS was not associated with the Stroop test in i-Share but showed a trend towards an association with poorer episodic memory performance in older community persons (N = 24,597, effect estimate ± SE: -0.19 ± 0.11, P = 0.08) 34 .

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nominally significantno p-value reported

For migraine and T2D in contrast there was evidence of residual pleiotropic effects (significant MR-Egger intercept, Supplementary Data 17 ) after removal of potentially pleiotropic outlier variants, and the association became only nominally significant for migraine.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.