In conclusion, there was a trend toward improved survival with ibrutinib and nivolumab in patients with DLBCL with elevated PD-L1, although the differences did not reach statistical significance.
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Biomarkers of response to ibrutinib plus nivolumab in relapsed diffuse large B-cell lymphoma, follicular lymphoma, or Richter's transformation.
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The sentences
Patients with DLBCL and PD-L1 elevation showed a trend toward improved response rates and prolonged survival with ibrutinib and nivolumab, with statistical significance reached for the association between PD-L1 expression and CR ( p = 0.028).