PD-L1 expression with respect to driver mutations in non-small cell lung cancer in an Asian population: a large study of 1370 cases in China.

Nonetheless, genetic alternations in ROS1, BRAF, RET , and MET showed a trend toward increased PD-L1 expression at lower cutoff values, but not at higher values, possibly due to the small number of positive cases involved.

also in 53,322 other papers

Nonetheless, our results were consistent in part with a previous study that showed a higher level of PD-L1 expression in patients harboring ROS1 rearrangements or MET mutations (using the 22C3 antibody, with a TPS cutoff at ⩾1% and ⩾50%), although the difference did not reach statistical significance. 23 In addition, that study also showed a similar level of PD-L1 expression regarding ALK rearrangements. 23 Nevertheless, our study did show a difference in PD-L1 expression with respect to different driver mutations and ethnic contexts.

also in 111,027 other papers