Furthermore, Kaplan-Meier analysis also demonstrated that patients with higher expression levels of LPCAT1 exhibited significantly shorter OS time compared with those with lower expression of LPCAT1 among total-AML and non-M3 AML cases, whereas a trend for LFS time was observed which did not reach statistical significance ( Fig. 1A and B ).
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Identification of <i>LPCAT1</i> expression as a potential prognostic biomarker guiding treatment choice in acute myeloid leukemia.
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The results of Cox regression univariate analysis revealed that LPCAT1/2/3 expression was associated with OS in AML, and LPCAT3 expression was associated with LFS, whereas LPCAT1/2 expression showed a trend being associated with LFS ( Table I ).