While the other two vessel types—CD31+ capillaries without lumen and α-SMA+ arterioles—failed to reach statistical significance, this may be attributed to the experiment’s duration (14 days) and a clear trend to pHGF/VEGF superiority was obvious.
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Therapeutic Angiogenesis by a "Dynamic Duo": Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle.
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