Remdesivir for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials.

Contemp Clin Trials · 2021 · PMC7789823 · PMID 33422642

Europe PMC DOI

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

[ 5 ] (double-blinded RCT) included patients with severe COVID-19 and showed a trend towards faster time to clinical improvement that did not reach statistical significance; however because this trial was stopped early (due to the decline in new cases in China), it may have been underpowered to detect an effect.

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a possible trendno p-value reported

It indicated a possible trend towards clinical benefit in remdesivir group and hence necessitating larger sample size for confirmation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.