Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models.

Finally, PSELT showed a clear tendency to preserve dopamine levels in the Str measured at day 7 post-treatment, but the difference between the PSELT/MPTP- and MPTP-treated groups did not reach statistical significance ( Fig. 5 J).

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In fact, PSELT exhibited a clear trend to normalize dopamine levels in the striatum after 7 days of treatment but the differences were not statistically significant likely due to the compensation phenomena.

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