Although the differences did not reach significance, there is a clear trend, probably caused by cross-reactivity between ZIKV and DENV.
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Pregnant Women Infected with Zika Virus Show Higher Viral Load and Immunoregulatory Cytokines Profile with CXCL10 Increase.
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The sentences
Interestingly, IL-1β seems to be downregulated in nonpregnant infected but upregulated in infected pregnant women; however, the difference did not reach statistical significance.