DCs obtained using monocytes that were cocultured with not activated platelets also showed defects in T cell stimulation to some extent but it did not reach statistical significance.
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Monocytes complexed to platelets differentiate into functionally deficient dendritic cells.
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The sentences
Type 1 DCs cocultured with CD40L and thrombin activated platelets showed a trend toward reduced levels of IL‐12 (not statistically significant, Fig. 4C ).