Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.

The dendritic expansion of Purkinje cells transfected with RGS8-GFP showed a trend toward decreasing dendritic tree size compared to non-transfected Purkinje cells in same culture well or Purkinje cells transfected with GFP tag alone, but the reduction did not reach statistical significance.

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