Thalamocortical connectivity is associated with autism symptoms in high-functioning adults with autism and typically developing adults.

In ASD males, a positive linear relationship approaching significance was noted between AQ total score and right thalamus–left precentral/postcentral gyrus RSFC ( r = 0.48, p = 0.079).

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After Bonferroni correction for five seeds, only the bilateral precentral and postcentral gyri retained a significant difference in mean parameter estimates between ASD and TD groups; the right superior parietal lobule was trending towards significance (Fig. 1B ).

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