Surgical treatment and neurological outcome of infiltrating intramedullary astrocytoma WHO II-IV: a multicenter retrospective case series.

J Neurooncol · 2021 · PMC7875841 · PMID 33094355

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0930

boldest claim

The sentences

failed to reach statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

Loss of nuclear ATRX expression showed a strong association with the WHO ( η 2 = 0.481) but failed to reach statistical significance ( p = 0.052) (Table 2 ).

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showed a trendp = 0.093so close (0.05 < p ≤ 0.1)

The differing mean values showed a trend of dependence on the WHO grade without reaching statistical significance ( p = 0.093) in ANOVA modeling.

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a positive trendno p-value reported

In spinal cord astrocytomas, radiotherapy failed to reach a statistically significant effect in most publications [ 29 , 33 ], although a positive trend has been described [ 22 ].

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highly significantno p-value reported

We did not observe any statistical association of surgical extent and survival, but, interestingly, we identified a highly significant prognostic clinical factor: the preoperative clinical status (classified via the modified McCormick grade) in univariate and multivariate testing.

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