Validation Analysis In a meta-analysis of 3 independent data sources, rs738409 G showed a trend for association with a reduced risk of COVID-19 hospitalization/severe disease vs mild disease; but the result did not reach statistical significance (additive OR: 0.83; 95% CI, 0.66–1.05; P = .12; P heterogeneity = .68) (see Figure 1 ).
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The rs738409 G Allele in PNPLA3 Is Associated With a Reduced Risk of COVID-19 Mortality and Hospitalization.
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