Unfavorable Dynamics of Platelet Reactivity during Clopidogrel Treatment Predict Severe Course and Poor Clinical Outcome of Ischemic Stroke.

All variables that reached a p -value less than 0.05 or showed a trend ( p <0.1) in univariate calculations were examined as the independent variables in multivariate models.

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However, the overall impact of clopidogrel nonresponsiveness, defined as a higher baseline value of platelet reactivity, on the severity, disability, deterioration, and early or late prognosis among stroke subjects did not reach statistical significance in our study, as estimated in logistic regression.

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