Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study.

Nutr Metab (Lond) · 2021 · PMC7923458 · PMID 33648550

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

a strong trendp = 0.066so close (0.05 < p ≤ 0.1)

Considering both families together, there was a strong trend ( p = 0.066) for more compounds to change baseline-to-KD in patients with an optimal vs. no observable clinical response.

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showed a trendno p-value reported

We did not replicate those findings, and in fact showed a trend for lower initial acetyl-carnitine in optimal responders (and a significant increase during KD was also specific to optimal responders – showing a strong regulation by KD).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.