Clinical efficacy of hyaluronate-containing embryo transfer medium in IVF/ICSI treatment cycles: a cohort study.

Hum Reprod Open · 2021 · PMC7937422 · PMID 33718621

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showed a trendno p-value reported

Our recent experimental study described an in vitro model of embryo implantation and showed a trend towards protracted attachment kinetics of blastocysts exposed to HA-rich ET medium (EmbryoGlue ® ) ( Ruane et al. , 2020 ).

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did not reach statistical significanceno p-value reported

The risk of early pregnancy loss tended to be reduced with the use of HA-rich culture medium relative to the use of low HA, independent of the duration of exposure: long HA exposure (OR = 0.76, 95% CI: 0.54–1.06), short HA exposure (OR = 0.84, 95% CI: 0.54–1.30), however, this did not reach statistical significance.

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