From Pathogenesis to Therapy in Knee Osteoarthritis: Bench-to-Bedside.

Whereas the decrement in WOMAC and VAS values were in favor of the O 2 –O 3 group, the differences compared to corticosteroid-treated patients did not reach statistical significance with respect to the reduction in joint effusion on ultrasound [ 148 ].

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While this was true for WOMAC pain score improvement at 4 weeks, the differences in mean VAS (Visual Analogue Scale) levels between the two study groups failed to reach statistical significance at the end of the follow-up period [ 133 ].

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