Preventing and Treating Neurological Disorders with the Flavonol Fisetin.

A strong trend toward earlier recovery in both the low- and high-dose fisetin-treated animals compared to placebo following both the pre- and post-stroke treatment strategies was also seen.

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While animals injected immediately before the onset of ischemia with 25 mg/kg of fisetin showed a trend towards smaller infarcts, animals treated with the higher dose of fisetin (50 mg/kg) had significantly smaller infarcts.

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