Novel <i><i>STMN2</i></i> Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype.

Once samples were stratified by the CA genotype, a distinct trend was observed in both patients and controls of decreasing STMN2 expression between the S/L and L/L samples, however this did not reach statistical significance ( Figure 3D ).

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When the cumulative survival percentage was analyzed using a Cox proportional hazards model, comparing L/L genotypes to other genotypes, the L/L group showed a trend toward decreased survival duration compared to those with at least one short allele.

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