Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach.

Lancet Psychiatry · 2021 · PMC8055541 · PMID 33740410

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1300

boldest claim

The sentences

nominally significantp<0·050actually significant

All showed a concordant effect direction between the GWAS prospective and GWAS retrospective (p=0·0005, binomial sign test), with six loci nominally significant (GWAS prospective p<0·050) and one significant after Bonferroni correction for the 12 loci (rs3851357, GWAS prospective p=0·0035).

also in 7,414 other papers

did not reach statistical significancep=0·13not close (p > 0.1)

By contrast, the difference in between-family and between-sibling PGS effects (passive gene–environment correlation) did not reach statistical significance (β=0·039 [SE 0·026]; p=0·13) accounting for approximately 42% of the total effect.

also in 103,338 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.