In Vivo Assessment of Metabolic Abnormality in Alport Syndrome Using Hyperpolarized [1-<sup>13</sup>C] Pyruvate MR Spectroscopic Imaging.

Metabolites · 2021 · PMC8067337 · PMID 33917329

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0750

boldest claim

The sentences

a strong trendp = 0.064so close (0.05 < p ≤ 0.1)

At 7-week-old, the KO group demonstrated a strong trend toward a lower level of both normalized lactate (0.17 ± 0.04) and Lac/Pyr (0.33 ± 0.10), as compared to the WT group (0.21 ± 0.05 for normalized lactate, p = 0.064; 0.42 ± 0.12 for Lac/Pyr, p = 0.056).

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showed a trendp = 0.075so close (0.05 < p ≤ 0.1)

Similarly, Lac/Pyr in the KO group showed a trend toward decrease over time (0.40 ± 0.15 at 4-week-old; 0.33 ± 0.10 at 7-week-old, p = 0.075).

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