Fear of pain moderates the relationship between self-reported fatigue and methionine allele of catechol-O-methyltransferase gene in patients with fibromyalgia.

PLoS One · 2021 · PMC8081450 · PMID 33909692

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0850

boldest claim

The sentences

a clear trend toward significancep = 0.056so close (0.05 < p ≤ 0.1)

Analyzes reveal a clear trend toward significance in the regression coefficient for fatigue (β = -0.212; p = 0.056).

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tendency towards significancep = 0.075so close (0.05 < p ≤ 0.1)

Specifically, the interaction effect between group and the COMT gene for fatigue remained significant [F (2,151) = 6.44; p = 0.002, η 2 p = 0.079], as well as maintaining a tendency towards significance for pain [F (2,174) = 2.629; p = 0.075, η 2 p = 0.029].

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did not reach statistical significancep = 0.085so close (0.05 < p ≤ 0.1)

Although a trend was identified for the interaction between Group and COMT genotypes for pain perception, it did not reach statistical significance [F (2,175) = 2.504; p = 0.085, η 2 p = 0.028].

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a statistical trendno p-value reported

However, these analyses did not show significant differences, only a statistical trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.